Tag: <span>RT-PCR</span>


Non-specific primers reveal false-negative risk in detection of COVID-19 infections

As an easy and rapid method to diagnose coronavirus virus, including SARS-CoV-2, SARS and so on, Reverse Transcription Polymerase Chain Reaction (RT-PCR) was commonly used to confirm COVID-19 infections worldwide. Some institutes or universities provided several RT-PCR assays to diagnose 2019-nCoV (previous name of COVID-19) and the protocols. Because of occurrence of abnormal results, several...


Why is chest CT important for early diagnosis of COVID-19?

COVID-19 diagnosis is based on the identification of viral RNA through Reverse Transcription Polymerase Chain Reaction (RT-PCR) from oral-nasopharyngeal swabs, which however presents suboptimal sensitivity and may require several hours in overstressed laboratories. These drawbacks have called for an additional, complementary first line approach. Computed Tomography (CT) Scan is the gold standard method for the...


Hematologic parameters in patients with COVID‐19 infection

As of 28 February, 2020, Singapore had 96 confirmed cases of COVID‐19 infection. SARS‐CoV‐2 was confirmed by Real Time Reverse Polymerase Chain Reaction (RT‐PCR), performed on respiratory samples of these patients. A majority of 69 out of these 96 patients were treated at the National Centre for Infectious Diseases (NCID). A new study presents a...